Latex agglutination test for staphylococcal toxic shock syndrome toxin 1
نویسندگان
چکیده
منابع مشابه
Staphylococcal toxic shock syndrome.
A 28 year old male presented with fever, tachycardia, generalized lymphadenopathy and diffuse rash over the body. He failed to respond to intravenous antibiotics and developed cardiogenic shock, multiple organ failure and died within six hours after hospitalization. Staphylococcus aureus colonies were revealed on blood culture.
متن کاملThe Staphylococcal Toxic Shock Syndrome
Toxic shock syndrome toxin 1 (TSST1)t is a 22-kD exotoxin produced by most strains ofStaphylococcus aureus isolated from patients with toxic shock syndrome (TSS) (1) . TSST1 is a potent activator of monocytes and T cells . It acts on monocytes to induce the synthesis of IL-1 and TNF (2-4) . TSSTl also triggers T cell activation and proliferation (5), as well as the production of large amounts o...
متن کاملStaphylococcal toxic-shock-syndrome-toxin-1 as a risk factor for disease relapse in Wegener's granulomatosis.
OBJECTIVES Nasal carriage of Staphylococcus aureus constitutes a risk factor for disease exacerbation in Wegener's granulomatosis (WG). We hypothesized that staphylococcal superantigens (SAg) are a determinant of S. aureus-related risk for disease relapse in WG. METHODS In a retrospective longitudinal cohort study in 62 WG patients, we investigated the presence of the staphylococcal SAg genes...
متن کاملEpithelial Proinflammatory Response and Curcumin-Mediated Protection from Staphylococcal Toxic Shock Syndrome Toxin-1
Staphylococcus aureus initiates infections and produces virulence factors, including superantigens (SAgs), at mucosal surfaces. The SAg, Toxic Shock Syndrome Toxin-1 (TSST-1) induces cytokine secretion from epithelial cells, antigen presenting cells (APCs) and T lymphocytes, and causes toxic shock syndrome (TSS). This study investigated the mechanism of TSST-1-induced secretion of proinflammato...
متن کاملImproved purification and biologic activities of staphylococcal toxic shock syndrome toxin 1.
An improved method for producing highly purified toxic shock syndrome toxin 1 (TSST-1) by preparative isoelectric focusing in a Bio-Rad Rotofor cell and then chromatofocusing is described. Purification to homogeneity was confirmed by silver staining after sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE; 50 micrograms of protein was loaded), by immunoblotting with polyclonal ...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 1986
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.23.3.509-512.1986